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Name of Collaboratory :

 

Inflammation and the Host Response to Injury

 
 

URL :

  http://www.gluegrant.org/  
 

Collaboratory Status :

 
Operational   Start Date : 2001 End Date : 2006 Info Last Updated : Tue, Dec 9 2003 2:01am PST
 
 

Primary Collaboratory Function :

  Distributed Research Center  
 

Secondary Collaboratory Functions :

   
 

Domain(s) :

  Clinical patient care, computational biology, bioinformatics, biostatistics, genomics, genetics  
 

Brief Description of the Collaboratory :

 

Inflammation and the Host Response to Injury is a research program supported by the National Institute of General Medical Sciences (NIGMS), a component of the National Institutes of Health. This large-scale collaborative program aims to uncover the biological reasons why patients can have dramatically different outcomes after suffering a traumatic injury. This research will help explain the molecular underpinnings that lead to organ injury and organ failure, while also helping to clarify how burn and trauma patients recover from injury. Inflammation and the Host Response to Injury is a discovery-driven research program led by a group of outstanding clinical scientists, computational biologists, bioinformatics specialists, biostatisticians, and experts in genomics and genetics.

Inflammation and the Host Response to Injury consists of a network of investigators from U.S. academic research centers. Participating institutions include hospitals that participate in clinical research studies, academic medical centers that perform analytical studies on blood and tissue samples, and informatics and statistics centers that develop databases and analyze data.

The program is organized into seven core groups. Each of the core groups is composed of a core director, participating investigators, and other experts. Core personnel are accomplished and highly successful basic scientists working in the areas of research relevant to the focus of each individual core. In addition to researchers who are experts in identifying and quantifying molecular events that occur after injury, the program includes experts who have not traditionally been involved in injury research but have been integrated into the program to expand the multi-disciplinary character of the team. These experts include biologists who are leaders in genome-wide expression analysis, engineers who are well recognized in genome-wide computational analysis, and bioinformatics experts who are leaders in the construction and analysis of large and complex relational databases. Program scientists are mutually supported by core resources that provide the expertise, technology, and comprehensive, consensus-based databases that will define the success of this program.

 
 

Access to Instruments :

   
 

Access to Information Resources :

  Information repository
Protocols
Standard Operating Procedures (SOP)
 
 

Access to People as Resources :

  Experts  
 

Funding Agency or Sponsor :

 
United States Department of Health and Human Services
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
 
 
 

Notes on Funding Agencies/Sponsors:

 
 
 
Organizations with Funded Participants:
 
Organization name:
Approx # of participants:
Description of organization's role(s):
Brigham and Womens Hospital
Participating Institution
University of Colorado System
   Denver Health / University of Colorado
Participating Institution
Northwestern University
   Feinberg School of Medicine
Participating Institution
Harvard University
   Harvard Medical School
Participating Institution
Massachusetts General Hospital
Awardee Institutions
Massachusetts Institute of Technology (MIT)
Participating Institution
Pacific Northwest National Laboratory (PNNL)
Participating Institution
University of Medicine and Dentistry of New Jersey
   Robert Wood Johnson Medical School
Participating Institution
Stanford University
Participating Institution
Loyola University Chicago
   Stritch School of Medicine
Participating Institution
University of Michigan
   UM School of Medicine
Participating Institution
University of Alabama School of Medicine
Participating Institution
University of Florida
Participating Institution
University of Pittsburgh
   University of Pittsburg Medical Center
Participating Institution
University of Rochester
   University of Rotchester Medical Center
Participating Institution
University of Texas Medical Branch
Participating Institution
University of Texas Medical School at Houston
Participating Institution
University of Texas Southwestern Medical Center at Dallas
Participating Institution
University of Washington
   UW School of Medicine
Participating Institution
Washington University in St. Louis
   Washington University School of Medicine
Participating Institution
 
TOTAL PARTICIPANTS:
 

Notes on Participants/Organizations:

   
     
 
 

Communications Technology Used :

  telephone
website
email
 
 

Technical Capabilities :

   
  Key Articles :    
 

Project-reported performance data :

   
  Images of the Collaboratory:  
dataflow
 
 
         
    
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