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Name of Collaboratory :


Broad Institute


URL :  

Collaboratory Status :

Operational   Start Date : 2003 End Date : Info Last Updated : Fri, Dec 3 2010 6:00pm PST

Primary Collaboratory Function :

  Distributed Research Center  

Secondary Collaboratory Functions :

  Virtual Learning Community  

Domain(s) :

  BIOLOGICAL/AGRICULTURAL SCIENCES >Biological Sciences >Biomedical Sciences, BIOLOGICAL/AGRICULTURAL SCIENCES >Biological Sciences >Cell Biology, BIOLOGICAL/AGRICULTURAL SCIENCES >Biological Sciences >Biological Immunology, BIOLOGICAL/AGRICULTURAL SCIENCES >Biological Sciences >Molecular Biology, BIOLOGICAL/AGRICULTURAL SCIENCES >Biological Sciences >Pathology, Human and Animal, BIOLOGICAL/AGRICULTURAL SCIENCES >Biological Sciences >Pharmacology, Human and Animal  

Brief Description of the Collaboratory :


The Broad Institute is a genomic medicine research center located in Cambridge, Massachusetts, United States. Although it is independently governed and supported as a 501(c)(3) nonprofit research organization, the institute is formally affiliated with the Massachusetts Institute of Technology, Harvard University and its affiliated hospitals.

The Broad Institute's scientific research programs include the:

* Cancer Program
* Program in Medical and Population Genetics
* Genome Biology and Cell Circuits Program
* Chemical Biology Program
* Metabolic Disease Initiative
* Infectious Disease Initiative
* Psychiatric Disease Initiative
* Computational Biology and Bioinformatics

The faculty and staff of the Broad Institute include physicians, geneticists, and molecular, chemical, and computational biologists. The Faculty currently includes nine Core Members, whose labs are primarily located within the Broad Institute, and 108 Associate Members, whose primary labs are located at one of the universities or hospitals.

The Institute’s organization is unique among biomedical research institutions. It encompasses three types of organizational units: core member laboratories, programs and platforms. Scientists within these units work closely together — and with other collaborators around the world — to tackle critical problems in human biology and disease.

Each core member of the Broad Institute leads a laboratory consisting of students, postdoctoral fellows and scientific staff. These laboratories are similar in structure and membership to laboratories at academic institutions. However, rather than being embedded in a single department, core member laboratories are physically adjacent to scientists from other disciplines and work collaboratively with researchers both within and outside of the institute across a range of critical projects.

The Broad Institute involves a wide range of faculty from throughout its partner institutions — MIT, Harvard University and the Harvard-affiliated hospitals. The Broad faculty includes core members and associate members. All associate members hold primary appointments in a "home department" at one of the partner institutions, but are deeply involved in the scientific work and culture of the Broad Institute.

Programs and Program Initiatives are intellectual communities that unite researchers around a shared scientific focus. They are comprised of core and associate members and their laboratories, as well as Broad Institute staff. Program scientists meet regularly to share ideas, launch collaborations that extend beyond the capabilities of any individual laboratory or institution, and pursue ambitious projects with the potential to transform their field.

Platforms and Platform Initiatives are professional organizations that bring together the technological, informatics and management expertise necessary to create unmatched capabilities for the Broad’s research. They are led by and comprised of professional staff scientists with deep scientific expertise, organizational skills, and experience executing projects that are far-reaching in scope and scale. Platform scientists routinely push the frontier of rapidly evolving technologies and pursue projects that could not be undertaken within a single academic laboratory.

The Broad Institute is dedicated to sharing their exciting new knowledge — and its social implications — with everyone. Through a variety of outreach activities, public programs, online educational resources, and events, they invite others to learn more about exciting discoveries that are unfolding and what this new knowledge means for them. Their outreach efforts currently include:

Diversity Initiative in Scientific Research
A series of hands-on programs encouraging underrepresented minorities at all levels of scientific training to pursue biomedical research.

Educational Outreach Program
An on-site program enabling local high school students and teachers to explore what it means to be a scientist.

A collection of unique, interactive science exhibits located in the Broad Institute’s 7 Cambridge Center building and geared toward a wide audience.

Midsummer Nights Science
Midsummer Nights Science is an annual lecture series that explores key advances in genomic research. This lecture series is held each summer and is open to the general public.

Look up terms related to the science that goes on at the Broad.


Access to Instruments :

  A central element of the Broads mission is the open sharing of the data they produce and the analytical software tools they develop with the entire scientific community, empowering researchers around the world to join us accelerating the transformation of medicine and biology.

Currently available data and tools can be found on the institutes Website.

Access to Information Resources :

  A central element of the Broads mission is the open sharing of the data they produce and the analytical software tools they develop with the entire scientific community, empowering researchers around the world to join us accelerating the transformation of medicine and biology.

Currently available data and tools can be found on the institutes Website.

Access to People as Resources :


Funding Agency or Sponsor :

Broad Foundations
United States Department of Health and Human Services
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
National Institute of General Medical Sciences (NIGMS)
National Institute of Environmental Health Sciences (NIEHS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Allergy and Infectious Diseases (NIAID)
National Human Genome Research Institute (NHGRI)
National Heart, Lung, and Blood Institute (NHLBI)
National Center for Research Resources (NCRR)
National Institute of Dental and Craniofacial Research
National Institute on Drug Abuse
National Institutes of Health Office of the Director
National Cancer Institute (NCI)
National Science Foundation (NSF)
United States Department of Agriculture (USDA)

Notes on Funding Agencies/Sponsors:
The Broad Institute receives 90 percent of its annual funding from US government agencies, but also receives some from private individuals. They also receive sponsored research support from several foundations.

Organizations with Funded Participants:
Organization name:
Approx # of participants:
Description of organization's role(s):
Beth Israel Deaconess Medical Center
Brigham and Womens Hospital
Childrens Hospital Boston
Dana-Farber Cancer Institute
Harvard University
   Harvard Medical School
   Faculty of Arts and Sciences (Harvard)
Massachusetts General Hospital
Massachusetts Institute of Technology (MIT)

Notes on Participants/Organizations:
The Broad Institutes deeply collaborative community includes more than 150 faculty and more than 1,500 scientists from across MIT, Harvard and the Harvard-affiliated hospitals working together to solve the most critical problems in biomedicine.

The Broad’s commitment to transforming human health also extends beyond the Boston area, and is reflected in the Institute’s rapidly growing number of international collaborations, including over 100 projects across more than 40 countries.

The Broad Institute has a Board of Directors consisting of 15 members, which "serve as wise and effective stewards of the institute, helping to drive the transformation of medicine that lies at the heart of the Broad Institutes mission."

They also have a Board of Scientific Counselors, consisting of 8 members, who "meet annually to review the institutes scientific progress over the past year and to provide advice on future scientific directions to the Institute Director and to the Board of Directors."


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