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Name of Collaboratory :

 

Competence Network Diabetes mellitus

 
 

URL :

  http://www.kompetenznetz-diabetes-mellitus.net/  
 

Collaboratory Status :

 
Operational   Start Date : 2010 End Date : Info Last Updated : Tue, Nov 2 2010 5:01am PDT
 
 

Primary Collaboratory Function :

  Distributed Research Center  
 

Secondary Collaboratory Functions :

  Community Data Systems  
 

Domain(s) :

  BIOLOGICAL/AGRICULTURAL SCIENCES >Biological Sciences >Biomedical Sciences, BIOLOGICAL/AGRICULTURAL SCIENCES >Biological Sciences >Pharmacology, Human and Animal  
 

Brief Description of the Collaboratory :

 

With the help of basic research projects, clinical and epidemiological studies and health service analysis, the members of the network hope to improve the knowledge regarding prevention, treatment and development of diabetes mellitus.

Seven research consortia with 24 projects have been selected for funding within the competence network diabetes mellitus:

Future Pediatric Diabetes (FPD)
Translational Research on the Early Pathogenesis and Prevention of Young-onset Diabetes (TREPPYD)
Advance Knowledge for Restoration of Beta Cells and Diabetes (AKROBAT)
Metabolomics / neue Biomarker
Diabetes-Collaborative Research of Epidemiologic Studies (DIAB-CORE)
Diabetes and Mental Aspects (DIAMANT)
Depression and cognition in diabetes. From neurobiological mechanisms to treatment strategies (DECODIA)

With these consortia and projects the competence network spans the fields of research from basic science via clinical and epidemiological studies to patient care and health economics. Due to pathogenic relations between diabetes and obesity the two competence networks for diabetes and obesity have established a close cooperation.

Speaker: Prof. Dr. Annette Ziegler, Munich

Member of the Technologie- und Methodenplattform für die vernetzte medizinische Forschung (TMF) collaboratory.

 
 

Access to Instruments :

   
 

Access to Information Resources :

  Expert committee IT platforms and meta-database

The aim is to establish a central database of patient cohorts in Germany. As a first step a central variable register will be established in order to design an optimal database for commonly used variables. As a second step data from patient cohort and trials will be entered into the central database so that analyses on large data sets are possible.

Expert committee workgroup biomarkers

The objective of this work group is to establish a platform that provides all network partners with standardised and validated protocols and methods as well as expertise to realize a harmonized phenotyping. The core aim of this working group consist of developing Standard Operating Procedures SOPs (sampling, processing, storage and preparation of samples) for harmonization of lab measurements and pre-analytics in all projects of the network. Workshops shall enable discussion of scientific aspects related to the topic of biomarkers, but enforce also validation and quality control of the elaborated SOPs and methods.
 
 

Access to People as Resources :

   
 

Funding Agency or Sponsor :

 
Federal Ministry of Education and Research (BMBF)
 
 
 

Notes on Funding Agencies/Sponsors:
Funding of the competence network is scheduled for 12 years. After the initial three years intentions are to increase yearly funding and to integrate new projects into the network.

 
 
 
Organizations with Funded Participants:
 
Organization name:
Approx # of participants:
Description of organization's role(s):
Albert-Ludwigs-Universität Freiburg
2
AKROBAT Consortium
Deutsches Diabeteszentrum (DDZ)
7
FPD/ DIAB-CORE Consortium
Forschungsinstitut der Diabetes Akademie Mergentheim (FIDAM)
3
DIAMANT Consortium
German Sport University Cologne
1
FPD Consortium
Hannover Medical School
1
FPD Consortium
Heinrich-Heine University Dusseldorf
3
AKROBAT/FPD Consortium
Helmholtz Zentrum München - German Research Center for Environmental Health
4
DIAB-CORE/Biomarker Consortium
Johannes-Gutenberg-Universitat Mainz
2
DECODIA Consortium
Justus-Liebig-Universität Giessen
1
DIAMANT Consortium
Kassenärztliche Vereinigung Bayerns (KVB)
3
TREPPYD Consortium
Klinikum Schwabing
1
TREPPYD Consortium
Leibniz Institute of Plant Genetics and Crop Plant Research (IPK)
1
AKROBAT Consortium
Martin-Luther-Universität Halle-Wittenberg
1
AKROBAT Consortium
Ruhr-Universitat Bochum
2
DECODIA Consortium
Technische Universität Dresden
4
TREPPYD/AKROBAT Consortium
Technische Universität München (TUM)
5
TREPPYD/Harmonisierung / Geschäftsstelle Consortium
Ulm University
3
FPD Consortium
Universität Bielefeld
1
FPD Consortium
Universität Duisburg-Essen
3
DIAB-CORE/DECODIA Consortium
Universität Lübeck
4
DECODIA Consortium
Universität Leipzig
3
FPD/DIAB-CORE Consortium
University of Greifswald
2
DIAB-CORE
University of Muenster
1
DIAB-CORE Consortium
University of Tubingen
6
Biomarker/DECODIA/Metabolomics Consortium
 
TOTAL PARTICIPANTS:
64
 

Notes on Participants/Organizations:
They have a steering committee and a scientific advisory board.

Across all seven consortia several work groups for thematic topics have been establised, which are aiming for methodoligical aspects important for more than one consortium. Core aims of these work groups are to establish common standards, to build up central measurement platforms, but also to advise network partners as well as to promote academic eduction.

Presently there are 4 work groups active:

Workgroup IT platforms and meta-database
Workgroup biomarker
Workgroup epidemiology, biometrics, and health economics
Workgroup mental aspects

   
     
 
 

Communications Technology Used :

   
 

Technical Capabilities :

   
  Key Articles :    
 

Project-reported performance data :

   
 
         
    
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